WNYC's radio program On the Media recently covered a few interesting issues related to accessibility and disability.
In their May 21st episode they discussed the decline in braille literacy and how this might effect the blind population in the US, accessibility issues on the internet and what it would take for all websites to become handicapped accessible, and accessible video games (including which mainstream games are the most popular with disabled players).
I downloaded the episode so you can listen to it on your iPod or computer. The accessibility issues are covered toward the end of the program. The file is pretty big so give it some time to download, or simply listen to it here:

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